contestada

Which of the following phase II metabolic reactions makes phase I metabolites readily excretable in urine?
A. Oxidation.
B. Reduction.
C. Glucuronidation.
D. Hydrolysis.
E. Alcohol dehydrogenation.

Respuesta :

C.  Glucuronidation.

Moreover, Phase II reactions consist of the addition of hydrophilic groups to the parent molecule, a toxic intermediate, or a nontoxic metabolite formed in Phase I that requires further transformation to increase its polarity. These reactions include conjugation reactions, glucuronidation, acetylation, and sulfation.

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